Frank Drebin is persuaded out of retirement to go undercover in a state prison. There he has to find out what top terrorist, Rocco, has planned for when he escapes. Adding to his problems, Frank's wife, Jane, is desperate for a baby.

At age 19, a young woman is jilted at the altar. This leads to a declaration that she will swear off men forever. Now 10 years later, she suddenly decides she would like to have a child. She advertises in the newspaper for potential mates, whether by traditional methods or by sperm donors, but gets nothing but losers. However, two neighborhood men vie for her attention - her gynecologist and a professional clown.