Top scientists work feverishly in a secret, state-of-the-art laboratory to discover what killed the citizens of a small town and how the deadly contagion can be stopped.

African-American Philadelphia police detective Virgil Tibbs is arrested on suspicion of murder by Bill Gillespie, the racist police chief of tiny Sparta, Mississippi. After Tibbs proves not only his own innocence but that of another man, he joins forces with Gillespie to track down the real killer. Their investigation takes them through every social level of the town, with Tibbs making enemies as well as unlikely friends as he hunts for the truth.

A team of top scientists work feverishly in a secret, state-of-the-art laboratory to discover what has killed the citizens of a small town and learn how this deadly contagion can be stopped.

A black police detective is asked to investigate a murder in a racially hostile southern town.

When virtually all of the residents of Piedmont, New Mexico, are found dead after the return to Earth of a space satellite, the head of the US Air Force's Project Scoop declares an emergency. Many years prior to this incident, a group of eminent scientists led by Dr. Jeremy Stone (Arthur Hill) advocated for the construction of a secure laboratory facility that would serve as a base in the event an alien biological life form was returned to Earth from a space mission. Stone and his team - Drs. Dutton, Leavitt and Hall (David Wayne, Kate Reid, and (James Olson, respectively)- go to the facility, known as Wildfire, and try to first isolate the life form while determining why two people from Piedmont (an old wino and a six-month-old baby) survived. The scientists methodically study the alien life form unaware that it has already mutated and presents a far greater danger in the lab, which is equipped with a nuclear self-destruct device should it manage to escape.