A cryptic phone call sets off a dangerous game of risks for Elliot, a down-on-his-luck salesman. The game promises increasing rewards for completing 13 tasks, each more sinister than the last.

After a couple of weeks seeking out his teenage daughter Maggie, Wade finds her in the quarantine wing of a hospital. Maggie has been infected by a lethal outbreak that transforms the victim into a zombie. Wade's friend Dr. Vern Kaplan releases Maggie to spend her last days with Wade and her family. Her stepmother Caroline asks Wade to take their little kids to her sister's house to keep them safe. While Maggie is slowly transformed, Wade stays with her, protecting her. But Dr. Vern warns him that the moment is coming closer and closer when he must make an ultimate decision.