While Andy's mother is admitted to a psychiatric hospital, the young boy is placed in foster care, and Chucky, determined to claim Andy's soul, is not far behind.

When foreman Frank shows new employee Freddy a secret military experiment in a supply warehouse in Louisville, Kentucky, the two klutzes accidentally release a gas that reanimates corpses into flesh-eating zombies. As the epidemic spreads throughout the town, and the creatures satisfy their hunger in gory and outlandish ways, Frank and Freddy fight to survive with the help of their boss and a mysterious mortician.

In 1988, Earth makes the first contact with an alien civilization. In 1991, these aliens, known as Newcomers, slowly begin to be integrated into human society after three years of quarantine.

While Andy's mother is admitted to a psychiatric hospital, the young boy is placed in foster care, and Chucky, determined to claim Andy's soul, is not far behind.