Eight college students travelling to Florida for Spring Break stumble into a remote town in Georgia, where they are set upon by the residents.

When a young woman disappears during Mardi Gras, her friends race to find her before she falls victim to a sadistic Southern family plagued by a centuries old voodoo curse.

The aristocratic, wealthy France-born Boudine family move to New Orleans in the mid-1800s to make their way in America. Then their beautiful youngest daughter cross paths with the fiancé of the legendary Queen of Louisiana Voodoo, Marie Laveau. They have a baby and try to keep it a secret, but Madame Laveau finds out and decides that the entire family deserves the focus of Laveau's most destructive curse.