A salesman (Keaton) rediscovers a lust for life after falling for the fiancée of his new business partner (Fraser), a Midwest transplant finding his footing in New York City.

A mafia boss and his family are relocated to a sleepy town in France under the witness protection program after snitching on the mob. Despite the best efforts of CIA Agent Stansfield (Tommy Lee Jones) to keep them in line, Fred Manzoni (Robert De Niro), his wife Maggie (Michelle Pfeiffer) and their children Belle (Dianna Agron) and Warren (John D'Leo) can't help but revert to old habits and blow their cover by handling their problems the "family" way, enabling their former mafia cronies to track them down. Chaos ensues as old scores are settled in the unlikeliest of settings.