A new assignment forces a top spy to team up with his football hooligan brother.

Tim Lippe has no idea what he's in for when he's sent to Cedar Rapids, Iowa to represent his company at an annual insurance convention, where he soon finds himself under the "guidance" of three convention veterans.

MI6's top assassin (Mark Strong) has a brother. Unfortunately for him, he's an English football supporter (Sacha Baron Cohen) from the town of Grimsby. Nobby has everything a man from the poor English fishing town of Grimsby could want - 9 children and the most attractive girlfriend in northern England (Rebel Wilson). There's only one thing missing in his life: his little brother, Sebastian. After they were adopted by different families as children, Nobby spent 28 years searching for him. Upon hearing of his location, Nobby sets off to reunite with his brother, unaware that not only is his brother an MI6 agent, but he's just uncovered a plot that puts the world in danger. On the run and wrongfully accused, Sebastian realizes that if he is going to save the world, he will need the help of its biggest idiot.

Tim Lippe (Helms) was the guy people always thought would go places but then he just ... didn't. He's been living in über-sleepy Brown Valley, Wisconsin his whole life, still "pre-engaged" to his 7th grade teacher Macy Vanderhei (Weaver), while selling insurance to protect other people's dreams. But now, Tim's stalled life is about to get a kick-start because, for the first time in his 34 years, he's headed to a "major" metropolis - Cedar Rapids, Iowa - where he must try to save his company at a do-or-die insurance convention that, for him, will be entirely unconventional. From the minute he checks into his hotel with his ancient American Tourister and cummerbund money belt, it's clear Tim has no idea how the modern world really works. He is soon smitten with seductive Nebraskan insurance agent Joan Ostrowski-Fox (Heche) and awed by his experienced roommates, the straight-shooting Ronald Wilkes (Whitlock Jr.) and the suspicious Dean Zeigler (Reilly). Disheartened when he comes ...