When three different animals become infected with a dangerous pathogen, a primatologist and a geneticist team up to stop them from destroying Chicago.

In the aftermath of a massive earthquake in California, a rescue-chopper pilot makes a dangerous journey with his ex-wife across the state in order to rescue his daughter.

Nash Bridges continues to run San Francisco's SIU in 2020 while confronting a changing city, a new boss, and a world in which police work focuses on modern data-crunching and predictive policing. Although the world around him has changed, Nash hasn't.

Primatologist Davis (Dwayne Johnson) shares an unshakable bond with George, the extraordinarily intelligent silverback gorilla who has been in his care since he was young. When a greed-fueled corporation's genetic experiment goes awry, George and other animals across the country are mutated into aggressive supercreatures who destroy everything in their path. In this adrenaline-filled ride, Davis tries to find an antidote, not only to halt a global catastrophe but also to save the fearsome creature who was once his friend.