A schoolteacher with a phobia of hospitals finds herself searching for her boyfriend inside one while teaming up with a man suffering the same ordeal that she's in.

In Guesta Verde University, the deranged Professor Curien is trying to bring back the dead, killing students for the experiment. There is an outbreak of zombies in the campus, and the government sends a NSA medical research team, formed by Dr. Alexandra Morgan a.k.a. Nightingale and lieutenant Ellis, with a special force leaded by lieutenant Dalton, trying to get the zero sample from the first generation zombie. The team has a very short time to accomplish their mission and leave the place before missiles are sent to destroy the area. However, the place is crowded of hyper sapiens and the group has to fight to survive.

A westerner named Casey, studying Ninjutsu in Japan, is asked by the Sensei to return to New York to protect the legendary Yoroi Bitsu, an armored chest that contains the weapons of the last Koga Ninja.