Ex-government operative Bryan Mills finds his life is shattered when he's falsely accused of a murder that hits close to home. As he's pursued by a savvy police inspector, Mills employs his particular set of skills to track the real killer and exact his unique brand of justice.

After witnessing her parents’ murder as a child in Bogota, Cataleya Restrepo grows up to be a stone-cold assassin. She works for her uncle as a hitman by day, but her personal time is spent engaging in vigilante murders that she hopes will lead her to her ultimate target: the mobster responsible for her parents' death.

The retired CIA agent Bryan Mills invites his teenage daughter Kim and his ex-wife Lenore, who has separated from her second husband, to spend a couple of days in Istanbul where he is working. Meanwhile, the patriarch of the community of the Albanian gang of human trafficking, Murad Krasniqi, seeks revenge for the death of his son and organizes another gang to kidnap Bryan and his family. Bryan and Lenore are abducted by the Albanians, but Kim escapes and is the only hope that Bryan has to escape and save Lenore.

A young woman grows up to be a stone-cold assassin after witnessing her parents' murder as a child in Bogota. She works for her uncle as a hitman by day, but her personal time is spent engaging in vigilante murders that she hopes will lead her to her ultimate target - the mobster responsible for her parents' death.