A car accident puts Paige in a coma, and when she wakes up with severe memory loss, her husband Leo works to win her heart again.

On a desolate stretch of desert highway, weary travelers - two men on the run from their past, a band on their way to the next gig, a man struggling to get home, a brother in search of his long-lost sister and a family on vacation - are forced to confront their worst fears and darkest secrets in a series of interwoven tales of terror and remorse on the open road.

Happy young married couple Paige and Leo are, well, happy. Then a car accident puts Paige into a life-threatening coma. Upon awakening she has lost the previous five years of memories, including those of her beloved Leo, her wedding, a confusing relationship with her parents, or the ending of her relationship with her ex-fiance. Despite these complications, Leo endeavors to win her heart again and rebuild their marriage.

As bass guitarist for a garage-rock band, Scott Pilgrim has never had trouble getting a girlfriend; usually, the problem is getting rid of them. But when Ramona Flowers skates into his heart, he finds she has the most troublesome baggage of all: an army of ex-boyfriends who will stop at nothing to eliminate him from her list of suitors.

Bruce Banner, a scientist on the run from the U.S. Government, must find a cure for the monster he turns into whenever he loses his temper.