A new street drug that sends its users across time and dimensions has one drawback: some people return no longer human. Can two college drop-outs save humanity from this silent, otherworldly invasion?

On a desolate stretch of desert highway, weary travelers - two men on the run from their past, a band on their way to the next gig, a man struggling to get home, a brother in search of his long-lost sister and a family on vacation - are forced to confront their worst fears and darkest secrets in a series of interwoven tales of terror and remorse on the open road.

Sweet Sarah, a struggling actress, is desperate to make it big in Hollywood's cut-throat film industry. Instead, she treads water waiting tables at a tacky fast-food restaurant. Eager for her big break, Sarah takes a chance on an ambitious horror movie, only to realise that dreams and reality are two entirely different things. As she catches the attention of a stone-faced casting director offering a second chance, Sarah must sacrifice everything in the name of art to seal the deal. But the question remains: How far is Sarah willing to go to catapult herself into the limelight?

It's a drug that promises an out-of-body experience with each hit. On the street they call it Soy Sauce, and users drift across time and dimensions. But some who come back are no longer human. Suddenly a silent otherworldly invasion is underway, and mankind needs a hero. What it gets instead is John and David, a pair of college dropouts who can barely hold down jobs. Can these two stop the oncoming horror in time to save humanity? No. No, they can't.