In 1957, lawyer James B. Donovan is recruited from his prestigious law firm to defend accused Soviet spy Rudolf Abel. It's an unenviable task in many respects. Donovan hasn't practiced criminal law since he was a prosecutor at the Nuremburg trials after World War II. Also, the strong anti-Communist mood at the time makes him a target from who think Abel should just be executed. Abel is convicted but Donovan convinces the judge to sentence him to prison, rather than execute him, as they may at some point in the future want to swap him for an American spy the Soviets might have in custody. Just such a scenario comes into play when in 1960 U-2 spy pilot Francis Gary Powers is shot down over Soviet territory and taken prisoner. Donovan is again recruited to act as the intermediary and negotiate swapping Able for the American requiring him to travel to East Berlin crossing the newly built Berlin Wall.

Teenagers Zach and Josh have been best friends their whole lives, but when a gruesome accident leads to a cover-up, the secret drives a wedge between them and propels them down a rabbit hole of escalating paranoia and violence.