Peter Parker is beset with troubles in his failing personal life as he battles a brilliant scientist named Doctor Otto Octavius.

Against the backdrop of grisly murders and child abductions, a clan of cannibalistic savages which plague the North-east Coast since 1858, is after an unsuspecting family and their innocent baby girl. Do they have what it takes to survive?

In 1989, the boy Martin Bristol has congenital insensitivity to pain with anhidrosis (CIPA), a rare neural disorder, in which the patient does not feel pain, heat or cold. He is abducted by the deranged serial-killer Graham Sutter (Brett Rickaby) and brought to the Sutter Meat & Poultry, an abandoned meat-packing plant in Minersville, Pennsylvania, where Graham slaughters young women that he kidnaps. Five years later, the stubborn seventeen year-old teenager Allison Miller loses her parents and moves to her uncle Jonathan Miller's house near the decrepit plant. Jonathan, his wife Karen and their little daughter Wendy welcome Allison, but the teenager does not give much attention to her new family. Allison likes to run alone on the road and she passes by the meat-packing plant and then she meets the mechanic William "Billy" and has a crush on him. Jonathan advises Allison to avoid running near the old factory and Billy, who is a problematic teenager. Allison does not listen to her uncle and brings tragedy to the Miller family.