The head of a high school reunion committee tries to get the most popular guy in school to attend their class' upcoming 20-year reunion.

After a couple of weeks seeking out his teenage daughter Maggie, Wade finds her in the quarantine wing of a hospital. Maggie has been infected by a lethal outbreak that transforms the victim into a zombie. Wade's friend Dr. Vern Kaplan releases Maggie to spend her last days with Wade and her family. Her stepmother Caroline asks Wade to take their little kids to her sister's house to keep them safe. While Maggie is slowly transformed, Wade stays with her, protecting her. But Dr. Vern warns him that the moment is coming closer and closer when he must make an ultimate decision.

For five friends, it was a chance for a summer getaway- a weekend of camping in the Texas Big Thicket. But visions of a carefree vacation are shattered with an accident on a dark and desolate country road. In the wake of the accident, a bloodcurdling force of nature is unleashed-something not exactly human, but not completely animal- an urban legend come to terrifying life...and seeking murderous revenge.