"Covert Affairs" centers on a young CIA operative, Annie Walker, mysteriously summoned to headquarters for duty as a field operative. While Annie believes she's been promoted for her exceptional linguistic skills, there may be something or someone from her past that her CIA bosses are really after. Auggie Anderson is a CIA military intelligence agent who was blinded while on assignment and is Annie's guide in this world of bureaucracy, excitement and intrigue.

Dr. Gregory House is a maverick physician who is devoid of bedside manner. While his behavior can border on antisocial, Dr. House thrives on the challenge of solving the medical puzzles that other doctors give up on. Together with his hand-picked team of young medical experts, he’ll do whatever it takes in the race against the clock to solve the case.