Violence comes to the isolated town of Fortitude in the Arctic Circle, one of the safest towns on Earth. As mysterious phenomena plague the town in the aftermath of a murder, the inhabitants realize that no one can be trusted... and all is not that it seems.

It is the 23rd Century and Earth's space empire exiles its prisoners off-planet. Or at least they did until a crew of fierce and adventurous female crims break free and go on the run, heading for Arcadia. The show follows Ash, a young flight cadet falsely imprisoned before becoming embroiled in an audacious prison break-out. Across their perilous escape through space, this disparate gang of dynamic women fight, fall in love and betray each other. But one thing is for certain, the further they travel from Earth, the closer they come to understanding who they truly are.

Raymond "Red" Reddington, one of the FBI's most wanted fugitives, surrenders in person at FBI Headquarters in Washington, D.C. He claims that he and the FBI have the same interests: bringing down dangerous criminals and terrorists. In the last two decades, he's made a list of criminals and terrorists that matter the most but the FBI cannot find because it does not know they exist. Reddington calls this "The Blacklist". Reddington will co-operate, but insists that he will speak only to Elizabeth Keen, a rookie FBI profiler.

Raymond "Red" Reddington, one of the FBI's most wanted fugitives, surrenders in person at FBI Headquarters in Washington, D.C. He claims that he and the FBI have the same interests: bringing down dangerous criminals and terrorists. In the last two decades, he's made a list of criminals and terrorists that matter the most but the FBI cannot find because it does not know they exist. Reddington calls this "The Blacklist". Reddington will co-operate, but insists that he will speak only to Elizabeth Keen, a rookie FBI profiler.

On March 21, 1963, the inmates and guards at Alcatraz prison mysteriously disappear. To cover up the problem, the government reported the prison has been closed because of unsafe conditions. A secret government unit was set up to find the prisoners. Now, in the present-day, the inmates begin returning - unaged and unaware of where they have spent the missing decades - and continue their criminal ways. They are acting out of character and appear to be searching for specific objects. A federal agent employs a police officer and a conspiracy theory novelist to help track them down.