Titled Damien, the drama centers on the Omen's young boy, Damien Thorn. Now an adult and haunted by his past, Damien is faced with a series of macabre events and must finally face his true destiny: He is the Antichrist.

When over-achieving medical resident Liv Moore attends a party that turns into a zombie feeding frenzy, she ends up joining the ranks of the living dead. Determined to pass as human despite her pale appearance and newly listless demeanor, Liv forms a plan to resist her drive to consume fresh human brains by taking a job at a coroner's office, where she can secretly snack on the brains of corpses delivered there. Soon discovering that she absorbs the memories of those she feeds on, she finds new purpose by posing as a psychic and working with a detective to help solve their murders.