Four years after graduation, an awkward high school genius uses his sister's boyfriend's Labor Day party as the perfect opportunity to make his move on his high school crush.

Driving cross-country, Ray and his wife and daughter stop at a highway rest area where his daughter falls and breaks her arm. After a frantic rush to the hospital and a clash with the check-in nurse, Ray is finally able to get her to a doctor. While the wife and daughter go downstairs for an MRI, Ray, exhausted, passes out in a chair in the lobby. Upon waking up, they have no record or knowledge of Ray's family ever being checked in.

A couple stops at a gas station, where their 6 y.o. daughter's arm is fractured. They hurry to a hospital. Something strange is going on there. The wife and daughter go missing.