Two years after M3GAN's rampage, her creator, Gemma, resorts to resurrecting her infamous creation in order to take down Amelia, the military-grade weapon who was built by a defense contractor who stole M3GAN's underlying tech.

Following the launch of her new novel, 35-year-old writer Kate is invited to speak at her alma matter by her former professor. After accepting the invitation, Kate finds herself deeply enmeshed in the lives of a group of college students.

Follow the lives of Viago (Taika Waititi), Deacon (Jonathan Brugh), and Vladislav (Jemaine Clement) - three flatmates who are just trying to get by and overcome life's obstacles-like being immortal vampires who must feast on human blood. Hundreds of years old, the vampires are finding that beyond sunlight catastrophes, hitting the main artery, and not being able to get a sense of their wardrobe without a reflection-modern society has them struggling with the mundane like paying rent, keeping up with the chore wheel, trying to get into nightclubs, and overcoming flatmate conflicts.