When his fiancée Lucy falls victim to a mysterious illness, Arthur Holmwood turns to a former rival in her affections - Dr John Seward - for help. Seward calls in his mentor, Professor Van Helsing, who quickly uncovers the terrifying truth; the "illness" that afflicts Lucy is in fact a vampire's curse, and the only cure is a fresh supply of human blood. The discovery of several bodies - each drained of their blood - forces Van Helsing and Seward into a race against time to destroy the curse once and for all.

In a remote hill top mansion, a mysterious stranger emerges from a thunderstorm in the night, seeking refuge with the Whipley family; four young adults ruled by their strict religious mother, and their troubled father, who has vanished the previous night - But perhaps the 'stranger' is more connected to this family and to the dark unknown history of the house than they could ever suspect, and as the visitor begins to cultivate sexual tensions and paranoia within the house, the devilishly erotic history of the Whipley family threatens to lure them deep into its lustful, violent madness once again.