Mike and Danny fly a cropduster, but because of Danny's gambling debts, a local sheriff takes custody of it. Trying to earn money, they hitch-hike to the World's Fair in Seattle and, while Danny tries to earn money playing poker, Mike takes care of a small girl whose father has disappeared. Being a ladies' man, he also finds the time to court a young nurse.

It is 1977, Dublin rocks to the music of Thin Lizzy and the world is stunned by the death of Elvis Presley. Frankie, caught between acne and adulthood, has just completed his final exams in school. Convinced he will fail, he survives the summer organising a beach party, having lustful thoughts about two girls he believes are unobtainable and fending off the advances from a visiting American family friend, all whilst coping with his oddball family.

The presidencies of Kennedy and Johnson, the Vietnam War, the Watergate scandal and other historical events unfold from the perspective of an Alabama man with an IQ of 75, whose only desire is to be reunited with his childhood sweetheart.

In 1932, two strangers are wrongfully convicted and develop a strong friendship in prison that lasts them through the 20th century.