The CIA's most dangerous former operative is drawn out of hiding to uncover more explosive truths about his past.

A man is picked up by a fishing boat, bullet-riddled and suffering from amnesia, before racing to elude assassins and attempting to regain his memory.

When Jason Bourne is framed for a CIA operation gone awry, he is forced to resume his former life as a trained assassin to survive.

Jason Bourne dodges a ruthless C.I.A. official and his Agents from a new assassination program while searching for the origins of his life as a trained killer.

Jason Bourne is again being hunted by the CIA. It begins when Nicky Parson a former CIA operative who helped Bourne who then went under and now works with a man who's a whistle blower and is out to expose the CIA's black ops. So Nicky hacks into the CIA and downloads everything on all their Black Ops including Treadstone which Bourne was a part of. And Heather Lee, a CIA agent discovers the hack and brings it to the attention of CIA Director Dewey, the man behind the Black Ops. He then orders Parsons be found and hopefully Bourne too.

The events in this movie take place around the same time as the events in The Bourne Ultimatum (2007). When a British reporter was writing an expose about Black Ops operations Treadstone and Black Briar, and the ones responsible for them are concerned. And when Jason Bourne, former Treadstone operative got the file on Treadstone and Black Briar and gave it to Pamela Landy who then passed it to the media. When the men behind Treadstone and Black Briar learn of this, they're concerned how this will affect other ops they have. They decide it's best to shut down all ops and make sure make everyone involved disappears. They try to take out Aaron Cross who is part of another op called Outcome, but he manages to survive. He then seeks out Dr. Marta Shearing who worked on him when he began. It seems part of the program is for all subjects to take medications but he has run out, which is why he seeks her. But someone tries to kill her. He saves her and she tells him, he should have stopped ...

Bourne is once again brought out of hiding, this time inadvertently by London-based reporter Simon Ross who is trying to unveil Operation Blackbriar--an upgrade to Project Treadstone--in a series of newspaper columns. Bourne sets up a meeting with Ross and realizes instantly they're being scanned. Information from the reporter stirs a new set of memories, and Bourne must finally, ultimately, uncover his dark past whilst dodging The Company's best efforts in trying to eradicate him.

After escaping from the emotional and physical pain he previously encountered. Jason Bourne and his girlfriend Marie begin a new life as far away as possible. But when an assassination attempt on Bourne goes horribly wrong, Bourne must re-enter the life he wanted to leave behind, in order to find out the truth why they are still after him.