A shy student trying to reach his family in Ohio, a gun-toting bruiser in search of the last Twinkie and a pair of sisters striving to get to an amusement park join forces in a trek across a zombie-filled America.

Two cannibals/health food diner owners are on a wacky quest to restore life to the five million year old goddess Shitaar. Aided by their uncle's brain and penis, the two set about getting the required parts - virgins, assorted body parts from whores, and the ingredients for a "blood buffet". Their adversaries are the police: the chief with a Russian accent, the "player" detective, and the new Yorker with an Australian accent.