A man imprisons his estranged junkie friend in an isolated cabin in the boonies of San Diego to force him through a week of sobriety, but the events of that week are being mysteriously manipulated.

A single mother struggling with drug addiction is taken hostage in her own apartment by a man on the run who has broken out of jail and murdered the judge assigned to his case.

Heroin addict Mark Renton stumbles through bad ideas and sobriety attempts with his unreliable friends -- Sick Boy, Begbie, Spud and Tommy. He also has an underage girlfriend, Diane, along for the ride. After cleaning up and moving from Edinburgh to London, Mark finds he can't escape the life he left behind when Begbie shows up at his front door on the lam, and a scheming Sick Boy follows.

Newly engaged Shelby John and Ruby Red want a fresh start after their struggles with addiction, but when Shelby discovers his beloved Ruby dead on their porch, he embarks on a vengeful killing spree of the dealers who supplied her. Armed with nothing but adrenaline and a nail gun, Shelby begins to unleash chaos on the town’s criminal underbelly, as he hunt’s down crime lord Coyote. Sheriff Church must race against the clock to put an end to Shelby's vigilante justice before the entire town descends into a bloodbath.