A lawman and a priest work together to battle demonic forces.

When a frightening wave of violence sweeps through New York City, troubled cop Sarchie fails to find a rational explanation for the bizarre crimes. However, his eyes are opened to a frightening alternate reality when renegade Jesuit priest Mendoza convinces him that demonic possession may be to blame for the gruesome murders. Together, they wage a valiant supernatural struggle to rid the city of an otherworldly evil.

In the fall of 1960, Father Thomas Riley and Father John Thornton were sent by the Vatican to investigate a miraculous event in an Irish home for 'fallen women', only to uncover something much more horrific.