"Left Behind" finds commercial airline pilot Ray Steele (Nicholas Cage) struggling to keep his passengers calm and his plane afloat after the Biblical Rapture strikes mid-flight. Meanwhile, GWN reporter Cameron "Buck" Williams (Chad Michael Murray) becomes Ray's reluctant co-pilot, and Ray's terrified daughter Chloe (Cassi Thomson) braves the chaos of the city streets in search of her brother and mother.

Having grown sick and tired of his centuries as Dracula's lackey, Renfield finds a new lease on life — and maybe even redemption — when he falls for feisty, perennially angry traffic cop Rebecca Quincy.

While vacationing at a remote cabin, a young girl and her two fathers are taken hostage by four armed strangers who demand that the family make an unthinkable choice to avert the apocalypse. With limited access to the outside world, the family must decide what they believe before all is lost.

For young Charley Brewster, nothing could be better than an old horror movie late at night. Two men move in next door, and for Charley with his horror movie experience, there can be no doubt that their strange behavior is explained by the fact that they are a vampire and his undead day guardian. The only one who can help him hunt them down is a washed-up actor, Peter Vincent, who hosts Charley's favorite TV show, Fright Night. Vincent doesn't really believe that vampires exist, but does it for the money...