After a Black Friday riot ends in tragedy, a mysterious Thanksgiving-inspired killer terrorizes Plymouth, Massachusetts - the birthplace of the holiday. Picking off residents one by one, what begins as random revenge killings are soon revealed to be part of a larger, sinister holiday plan.

An 18-year-old high school girl is left at home by her parents and decides to have a slumber party. Meanwhile, a mass murderer with a propensity for power tools has escaped from prison, and eventually makes his way to the party where the guests begin dropping off one by one.

Two decades after surviving a massacre on October 31, 1978, former baby sitter Laurie Strode finds herself hunted by persistent knife-wielder Michael Myers. Laurie now lives in Northern California under an assumed name, where she works as the headmistress of a private school. But it's not far enough to escape Myers, who soon discovers her whereabouts. As Halloween descends upon Laurie's peaceful community, a feeling of dread weighs upon her -- with good reason.

Six years ago, Michael Myers terrorized the town of Haddonfield, Illinois. He and his niece, Jamie Lloyd, have disappeared. Jamie was kidnapped by a bunch of evil druids who protect Michael Myers. And now, six years later, Jamie has escaped after giving birth to Michael's child. She runs to Haddonfield to get Dr. Loomis to help her again.

One year after the events of Halloween 4: The Return of Michael Myers (1988), the Shape returns to Haddonfield once again in an attempt to kill his now-mute niece.