In the South Pacific island of Makatea, career-driven magazine editor Robin Monroe is on a week-long vacation getaway with her boyfriend, Frank Martin. An emergency work assignment in neighboring Tahiti requires Robin to hire the cantankerous pilot Quinn Harris who had flown them to Makatea on a small transport plane. While flying, a powerful storm forces Quinn to make an emergency landing on a nearby deserted island. The dissimilar pair avoid each other at first, until they're forced to team up to escape from the island -- and some pirates who want their heads.

Kate and Martin escape from personal tragedy to an Island Retreat. Cut off from the outside world, their attempts to recover are shattered when a Man is washed ashore, with news of airborne killer disease that is sweeping through Europe.