In the late 1960s, just for a lark, graduate student Eddie Jessup, known for being unconventional, brilliant and slightly mad, conducts experiments with an isolation chamber, using himself as the subject. His experiences in the chamber cause him to hallucinate, much of the imagery being religious-based although he's not religious. Seven years later, he is a respected full professor in the Harvard Medical School. Believing he has lost his edge and fallen into an unwanted state of respectability, Eddie decides to resume his work with sensory deprivation, this time using hallucinogens, specifically untested ones used in mystical Mexican rituals, to enhance the isolation-take experience. After initial tests, he claims he entered an alternate physical and mental state. Although unbelieving of Eddie's claims, his colleagues Arthur Rosenberg and Mason Parrish, as well as Eddie's wife Emily, herself a respected academic, are concerned for Eddie's well being. However, if Eddie's claims are indeed true, he could do irreparable harm to himself and others around him, especially if his altered states are uncontrollable.

A troubled college freshman, Luke, suffers a violent family trauma. He then resurrects his charismatic childhood imaginary friend Daniel to help him cope, not realizing how dangerous Daniel is.

An insurance investigator begins discovering that the impact a horror writer's books have on his fans is more than inspirational.

A group of heavily armed hijackers board a luxury ocean liner in the South Pacific Ocean to loot it, only to do battle with a series of large-sized, tentacled, man-eating sea creatures who had already invaded the ship.

After murdering her young patient, a once-esteemed psychiatrist helplessly watches her life spiral into a nightmarish maelstrom of supernatural hysteria and gruesome deaths, all linked to a seemingly unstoppable ancient curse.

The discovery of a massive river of ectoplasm and a resurgence of spectral activity allows the staff of Ghostbusters to revive the business.

A man struggles with memories of his past, which include a wife he cannot remember and a nightmarish world no one else ever seems to wake up from.

During an archaeological expedition on Bouvetøya Island in Antarctica, a team of archaeologists and other scientists find themselves caught up in a battle between the two legends. Soon, the team realize that only one species can win.

A mysterious artifact is unearthed in London, and famous scientist Bernard Quatermass is called into to divine its origins and explain its strange effects on people.

The discovery of a massive river of ectoplasm and a resurgence of spectral activity allows the staff of Ghostbusters to revive the business.

A crew of oceanic researchers working for a deep sea drilling company try to get to safety after a mysterious earthquake devastates their deepwater research and drilling facility located at the bottom of the Mariana Trench.

When their computer hacker friend accidentally channels a mysterious wireless signal, a group of co-eds rally to stop a terrifying evil from taking over the world.

When the night falls, and the creatures of the dark are crawling out of the shadows, there is only one man who stands between us and evil: Edward Carnby.

A detective of the paranormal slowly unravels mysterious events with deadly results.