In the late 1960s, just for a lark, graduate student Eddie Jessup, known for being unconventional, brilliant and slightly mad, conducts experiments with an isolation chamber, using himself as the subject. His experiences in the chamber cause him to hallucinate, much of the imagery being religious-based although he's not religious. Seven years later, he is a respected full professor in the Harvard Medical School. Believing he has lost his edge and fallen into an unwanted state of respectability, Eddie decides to resume his work with sensory deprivation, this time using hallucinogens, specifically untested ones used in mystical Mexican rituals, to enhance the isolation-take experience. After initial tests, he claims he entered an alternate physical and mental state. Although unbelieving of Eddie's claims, his colleagues Arthur Rosenberg and Mason Parrish, as well as Eddie's wife Emily, herself a respected academic, are concerned for Eddie's well being. However, if Eddie's claims are indeed true, he could do irreparable harm to himself and others around him, especially if his altered states are uncontrollable.

Bruce Banner, a genetics researcher with a tragic past, suffers a lab accident that makes him transform into a raging, giant green monster when angered, making him a target of forces seeking to abuse his power.

A newly married happy couple visits a sex therapist to determine why the wife can't achieve an orgasm with her husband. This causes a horrific suppressed memory to emerge and she becomes more and more distant.

Mark marries Marnie although she is a habitual thief and has serious psychological problems, and tries to help her confront and resolve them.

Tensions rise within an asbestos cleaning crew as they work in an abandoned mental hospital with a horrific past that seems to be coming back.

Dave Buznik is a businessman who is wrongly sentenced to an anger management program, where he meets an aggressive instructor.

When the US government attempts to weaponize the power of a possessed woman, they soon discover that there are forces that exist in this world that simply cannot be controlled.

In 1961, famed social psychologist Stanley Milgram conducted a series of radical behavior experiments that tested ordinary humans' willingness to obey authority.

Harvard symbologist Robert Langdon works with a nuclear physicist to solve a murder and prevent a terrorist act against the Vatican during one of the significant events within the church.

A group of strangers find themselves trapped in a maze-like prison. It soon becomes clear that each of them possesses the peculiar skills necessary to escape, if they don't wind up dead first.

Following an unexpected tragedy, a child psychologist named Malcolm Crowe meets an nine year old boy named Cole Sear, who is hiding a dark secret.

A murder inside the Louvre, and clues in Da Vinci paintings, lead to the discovery of a religious mystery protected by a secret society for two thousand years, which could shake the foundations of Christianity.

An agoraphobic psychologist and a female detective must work together to take down a serial killer who copies serial killers from the past.

A group of college seniors spending a weekend at a cottage for a psychological experiment called "fear therapy" find a lifelike wooden figure called Morty, which triggers everyone's deepest and darkest secrets and emotions.

Ferdinand Waldo Demara Jr. is a versatile man who gets his kicks out of impersonating a marine, a monk, a navy surgeon and a prison warden, eventually getting in trouble with the law for it.